Simply pharm: sistema para análise da complexidade de prescrições médicas e acompanhamento da adesão terapêutica

Abstract

Abstract—The growing complexity of pharmacotherapeutic regimens, driven by population aging and polypharmacy in the management of chronic diseases, increases the risk of adverse events and compromises medication adherence. The Medication Regimen Complexity Index (MRCI) allows this burden to be objectively measured; however, its manual calculation is timeconsuming and impractical in routine care, and electronic health records rarely automate it or integrate it with adherence monitoring. This work aimed to develop Simply Pharm, a web platform that automates the MRCI calculation and integrates it with the longitudinal monitoring of patients’ medication adherence and clinical progress. The system transparently displays the weights of each regimen component, links prescriptions to the CID-11 classification, records clinical progress through the SOAP method, and generates exportable analytical reports. The initial version of the tool was applied in a real clinical study with 267 neurological patients, supporting the stratification of therapeutic complexity; the correctness of the calculation was confirmed by manually recalculating a subsample, with 100% exact agreement. The results showed that automation removes the barrier of manual tabulation and enables large-scale analysis, constituting a tool to support clinical decision-making and patient safety.